Staying healthy while traveling · Madagascar

Hello, We’re planning to spend 3 months in Madagascar starting in mid-February. Areas: Mahajanga, Tulear, Diego Suarez, and Sainte Marie—the order isn’t set yet. We’ll either drive for part of the trip or take flights. We’ve heard all sorts of things about required vaccines and medications (is anti-malarial mandatory?). What’s the exact situation for travelers? I’ll come back to you for other topics (like finding a reliable driver, among others). Thank you. Best wishes to you all, Nicole